TRANSLATIONAL PHYSIOLOGY Rhythmic changes in colonic motility are regulated by period genes
نویسندگان
چکیده
Willemijntje A. Hoogerwerf, Vahakn B. Shahinian, Germaine Cornélissen, Franz Halberg, Jonathon Bostwick, John Timm, Paul A. Bartell, and Vincent M. Cassone Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan; University of Minnesota, Halberg Chronobiology Center, Minneapolis, Minnesota; Department of Poultry Science, Pennsylvania State University, University Park, Pennsylvania; Department of Biology, University of Kentucky, Lexington, Kentucky
منابع مشابه
Rhythmic changes in colonic motility are regulated by period genes.
Human bowel movements usually occur during the day and seldom during the night, suggesting a role for a biological clock in the regulation of colonic motility. Research has unveiled molecular and physiological mechanisms for biological clock function in the brain; less is known about peripheral rhythmicity. This study aimed to determine whether clock genes such as period 1 (per1) and period2 (p...
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